TRAJECTORY OF POST-COVID SELF-REPORTED FATIGUE AND DYSPNOEA IN INDIVIDUALS WHO HAD BEEN HOSPITALIZED BY COVID-19: THE LONG-COVID-EXP MULTICENTER STUDY

Trajectory of Post-COVID Self-Reported Fatigue and Dyspnoea in Individuals Who Had Been Hospitalized by COVID-19: The LONG-COVID-EXP Multicenter Study

Trajectory of Post-COVID Self-Reported Fatigue and Dyspnoea in Individuals Who Had Been Hospitalized by COVID-19: The LONG-COVID-EXP Multicenter Study

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Fatigue and bilstein shocks jeep xj dyspnoea are common post-COVID symptoms.The aim of this study was to apply Sankey plots and exponential bar plots for visualizing the evolution and trajectory of post-COVID fatigue and dyspnoea symptoms in a cohort of previously hospitalized COVID-19 survivors.A total of 1266 previously hospitalized patients due to COVID-19 participated in this multicentre study.They were assessed at hospital admission (T0), 8.4 months (T1), 13.

2 months (T2) and 18.3 months (T3) after hospital discharge and were asked about the presence of self-reported fatigue or dyspnoea symptoms.Fatigue was defined as a self-perceived feeling of constant tiredness and/or weakness whereas dyspnoea was defined as a self-perceived feeling of shortness of breath at rest.We specifically asked for fatigue and dyspnoea that participants attributed to the infection.Clinical/hospitalization data were collected from hospital medical records.

The prevalence of post-COVID fatigue was 56.94% (n = 721) at T1, 52.31% (n = 662) at T2 and 42.66% (n = 540) at T3.The prevalence of dyspnoea at rest decreased from 28.

71% (n = 363) at hospital admission (T0), to 21.29% (n = 270) at T1, to 13.96% (n = 177) at T2 and 12.04% (n = 153) at T3.The Sankey plots revealed that 469 (37.

08%) and 153 (12.04%) patients exhibited fatigue and dyspnoea at all follow-up periods.The recovery exponential curves show a decreased prevalence trend, showing that fatigue and dyspnoea recover the following three years after hospitalization.The regression models revealed that the female sex and experiencing the symptoms (e.g.

, fatigue, dyspnoea) at T1 were factors associated with the presence of post-COVID fatigue or dyspnoea at T2 and T3.The use of Sankey wilds of eldraine prerelease guide plots shows a fluctuating evolution of post-COVID fatigue and dyspnoea during the first two years after infection.In addition, exponential bar plots revealed a decreased prevalence of these symptoms during the first years after.The female sex is a risk factor for the development of post-COVID fatigue and dyspnoea.

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